Data on patients with inflammatory bowel disease (IBD) and depression and their unaffected siblings could shed light on the gut-brain axis influence on the pathophysiology of IBD.
A team, led by Bing Zhang, MD, Department of Medicine, Division of Gastrointestinal and Liver Disease, Keck School of Medicine, University of Southern California, identified the risk of depression among patients with IBD and their unaffected siblings, as well as the risk of IBD among patients with depression and their unaffected siblings.