Pre-existing fecal microbiome diversity was unaffected by gluten challenge in patients with celiac disease and nonceliac gluten sensitivity, according to data published in Clinical and Translational Gastroenterology.
“Investigations of celiac disease (CD) have posited a role of the gut microbiome in multiple aspects of disease development and progression,” Yael R. Nobel, MD, a gastroenterology and hepatology fellow at Columbia University Irving Medical Center in New York City, and colleagues wrote. “Certain taxa, including Bifidobacterium and Clostridial species such as Faecalibacterium prausnitzii, have decreased abundance in patients with active CD or treated CD compared with controls.”