Sanford Health implemented an AI-driven risk model in its EHR to enhance colorectal cancer screening for 100,000 newly eligible patients following the USPSTF recommendation to begin screenings at age 45. The AI tool analyzes 85 nontraditional risk factors, increasing cancer detection rates fivefold compared to traditional models. It also prioritizes high-risk patients for colonoscopies and integrates at-home stool DNA tests to optimize screening backlogs. The next phase will expand the AI tool across all primary care clinics, with broader applications in early disease detection beyond colorectal cancer.
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