World’s first ‘poop pill’ to undergo trial to treat advanced pancreatic cancer in Canada (Interesting Engineering)

Scientists at Lawson Research Institute and London Health Sciences Centre Research Institute are pioneering a fecal microbiota transplantation (FMT) approach to improve chemotherapy response in advanced pancreatic cancer. The Phase I trial will use LND101 capsules, containing gut microbes from healthy donors, to modify tumor microbiomes and enhance immune function. Previous studies on melanoma, lung, and renal cancer suggest this treatment could improve survival rates, marking a potential breakthrough in cancer therapy.