A randomized trial involving over 4,000 patients in FQHCs demonstrated the effectiveness of centralized mailed FIT kits and navigation for CRC screening. Led by researchers from the University of North Carolina, the study found that CRC screening completion was three times higher in the intervention group compared to usual care. The centralized approach overcame challenges typical in non-integrated care settings, such as resource limitations and care fragmentation. With higher detection of advanced colorectal neoplasia and increased colonoscopy completion rates, the intervention highlights the potential of organized outreach to bridge gaps in preventive care for underserved populations. Future studies will focus on cost and scalability to expand this model.
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