A large population-based study adds compelling real-world evidence that organized FIT-based colorectal cancer screening can significantly reduce deaths from colorectal cancer over time. Researchers found mortality began declining within three years of the program’s launch, with analyses suggesting a 42% relative reduction in CRC deaths compared with projected trends without screening. High participation rates, consistent annual follow-up, and timely diagnostic colonoscopy after positive FIT results were identified as key drivers of success, reinforcing the value of well-organized screening programs as colorectal cancer incidence continues to rise globally.
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