A new ranking of America’s most innovative companies highlights a broad shift in how innovation is defined in healthcare—spanning not just new products, but processes and culture. From pharma giants to health systems and AI startups, 53 healthcare organizations made the list, reflecting innovation across the entire care continuum. What stands out is that innovation is no longer limited to breakthrough therapies. It now includes digital transformation, operational efficiency, and the ability to embed innovation into organizational culture. The implication is clear: In healthcare, innovation is becoming less about isolated breakthroughs—and more about system-wide capability.
Author: Abhay Panchal
Delayed resumption of direct oral anticoagulants following outpatient colonoscopy was associated with higher thromboembolic risk without a reduction in gastrointestinal (GI) bleeding, according to a cohort study published in Clinical Gastroenterology and Hepatology. Management of anticoagulation around colonoscopy remains a common clinical challenge. Temporary interruption reduces post-procedural bleeding risk, but prolonged interruption may increase the risk of stroke and other thromboembolic events, noted Lawrence Jun Leung, MD, MPH, and colleagues. “Currently, little is known about the optimal timing for DOAC resumption after colonoscopy to minimize the risks of both gastrointestinal bleeding and thromboembolic events, and the lack of an evidence…
At the 2026 Gut Microbiota for Health World Summit, one theme stood out clearly: despite increasingly sophisticated tools like AI, metabolomics, and sequencing, the foundations of gut health remain remarkably simple. Across sessions, researchers repeatedly emphasized that dietary patterns—not supplements, testing, or personalization—continue to drive the most meaningful changes in the microbiome. The Mediterranean diet, in particular, remains one of the most consistently validated approaches, associated with greater microbial diversity, improved metabolite production, and reduced inflammation. What’s evolving is not the core advice, but the depth of understanding. Concepts like the “plant food matrix” and microbial metabolites are helping explain…
Guidance alerting endoscopists to adjust their peripheral gaze significantly improved adenoma detection in colonoscopies — particularly for flat lesions — regardless of the endoscopist’s experience level and without increasing procedure time, according to a recent study in Clinical Gastroenterology and Hepatology. The study was led by Fumiaki Ishibashi, PhD, with the Department of Gastroenterology at the International University of Health and Welfare Ichikawa Hospital in Chiba, Japan. In the study, a real-time eye-tracking system monitored endoscopists’ gaze and prompted them to look at the peripheral area.
The chief executive of America’s largest public hospital system says he is prepared to start replacing radiologists with artificial intelligence in some circumstances, once the regulatory landscape catches up. Mitchell H. Katz, MD, president and CEO of NYC Health + Hospitals, recently spoke during a panel discussion held by Crain’s New York Business. The trained internal medicine specialist noted how AI is increasingly being used to interpret mammograms and X-rays. This presents an opportunity to save on how much hospitals spend on radiologists, who have become more costly amid rising demand for imaging, Crain’s reported Thursday. “We could replace a…
One of the most persistent breakdowns in healthcare isn’t diagnosis—it’s execution. Even when clinicians make the right treatment decision, delays in prescriptions, prior authorizations, and affordability often prevent patients from getting timely care. A new partnership between OpenEvidence and Tandem is targeting exactly this gap—connecting evidence-based clinical decision-making directly to automated prescription fulfillment and prior authorization workflows. OpenEvidence brings real-time, AI-powered clinical guidance used in over a million consultations daily, while Tandem automates the downstream process—handling prior authorizations, appeals, pharmacy routing, and cost support. The result is a shift from fragmented steps to a continuous, end-to-end care pathway. This matters…
A new study suggests current standards for GI fellowship training in the U.S. may no longer be enough.Productivity-based compensation in academic medical centers has affected the time available for procedural training, and post-fellowship assessment remains focused on written exams rather than hands-on skills. Sri Komanduri, MD, associate chief of the division of gastroenterology and hepatology at Northwestern Medicine in Chicago, conducted a study to evaluate whether simulation could help close the gap. His team’s findings, published in Gastroenterology with funding from the National Institutes of Health, suggest it can.
The intersection of AI and gut health is attracting massive consumer interest—and capital. Over $500 million flowed into gut health startups last year, as patients increasingly turn to AI tools for answers about digestion, diet, and microbiome health. But beneath the momentum lies a fundamental tension: AI is scaling faster than scientific understanding of the microbiome. Startups are building products that promise personalized insights—from stool analysis to microbiome-based diet plans—but the biology they rely on remains deeply complex and, in many cases, poorly understood. The gut microbiome is influenced by countless variables, from diet and stress to environment, making it…
Recruitment for randomized controlled trials (RCTs) in inflammatory bowel disease (IBD) is challenging, with the average number of patients randomized per site per month declining significantly between 1998 and 2020 from 0.32 to 0.12 in ulcerative colitis (UC) and from 0.65 to 0.08 in Crohn’s disease (CD) (1). Prolonged enrollment increases trial costs and limits availability of new therapies for patients. Trial execution is hindered by substantial operational burdens placed on investigative sites, including study-specific training, administrative tasks (contracting, budget negotiations, regulatory documentation), and inconsistent prescreening workflows. These inefficiencies contribute to delayed site activation, slow patient enrollment, and underperformance across…
Gastric polyps are among the most commonly encountered lesions detected during upper endoscopy. These lesions encompass a range of histologic subtypes, including fundic gland polyps, gastric hyperplastic polyps, hamartomatous polyps, gastric adenomas, pyloric gland adenomas, oxyntic gland adenomas, and gastric neuroendocrine tumors. AGA’s newest clinical practice update provides a comprehensive framework for understanding the natural history and epidemiology of gastric polyps. It also offers guidance on best practices for endoscopic detection and classification, resection, and post-resection surveillance. Watch as Drs. Anna Buchner and Hashem El-Serag discuss gastric polyp detection and review the most common types identified in clinical practice.