A negative result on a screening colonoscopy appears to be highly predictive of no colorectal cancer even when screening intervals exceed 10 years, according to a recent large study. The finding suggests it may be safe to extend the currently recommended screening interval beyond 10 years in patients with a negative exam, particularly those considered to be at low risk.
“This is a very positive study because it really demonstrates the protective power of colonoscopy for substantial periods of time,” said Douglas K. Rex, MD, MASGE, a distinguished professor emeritus at the University of Indiana School of Medicine, in Indianapolis.