The American Gastroenterological Association has launched Nigel, an AI-powered virtual assistant designed specifically for gastroenterology and hepatology, providing clinicians with rapid, evidence-based answers grounded in AGA clinical guidelines. Unlike general-purpose AI tools, Nigel is built on peer-reviewed guidance using the GRADE evidence framework and offers transparent recommendations that include the strength of evidence and areas of uncertainty.
The tool is designed to support point-of-care clinical decision-making by summarizing guidelines, interpreting evidence, validating diagnostic and treatment approaches, and reducing the time clinicians spend searching the literature. With a knowledge base that updates as new AGA guidance is published, Nigel reflects the growing shift toward specialty-specific AI assistants that deliver trusted, guideline-driven clinical support rather than broad, internet-trained responses.