New gastrointestinal hamartomatous polyposis syndromes guideline (June 2022)
The United States Multi-Society Task Force (USMSTF) for Colorectal Cancer has published a new clinical guideline on the diagnosis and management of gastrointestinal hamartomatous polyposis syndromes [1]. In patients with Peutz-Jeghers syndrome, the guideline suggests upper gastrointestinal endoscopy and colonoscopy starting between 8 and 10 years of age and video capsule beginning at age 8 years. It also suggests screening for pancreatic cancer with alternating magnetic resonance imaging/magnetic resonance cholangiopancreatography or endoscopic ultrasound of the pancreas every one to two years, beginning at age 35 years. Our approach is consistent with the guideline.