Authored by gastroenterologist Aasma Shaukat, MD, MPH, this commentary argues that while blood-based colorectal cancer screening tests are gaining attention for their convenience, they should not replace colonoscopy or stool-based screening for most patients. The author explains that current blood tests are less effective at detecting early-stage cancers and precancerous polyps, making them a less reliable first-line screening option.
Shaukat recommends reserving blood-based tests for patients who decline or cannot complete recommended screening methods, with clear discussions about their limitations. Until stronger evidence and implementation frameworks are available, she urges practices to prioritize proven screening strategies while carefully evaluating where blood-based tests can add value.