‘Gut-on-a-chip’ promises breakthroughs in health research (National University of Singapore)

Scientists at NUS have developed Gut-Microbiome on a Chip (GMoC)—a 3D microgut model that mimics human intestines, allowing researchers to study gut microbes and their role in health and disease more accurately. The chip replicates gut structures, oxygen levels, and food movement, making it a scalable, realistic tool for investigating microbial interactions, immune responses, and potential therapeutic targets. Researchers aim to refine and commercialize the technology, paving the way for breakthroughs in gut microbiome research and disease prevention. The article gives insights on how GMoC could transform microbiome studies.