The American Gastroenterological Association (AGA) issued no formal recommendation on the use of AI-assisted colonoscopy (CADe) in adults, citing very low certainty of evidence regarding critical long-term outcomes such as colorectal cancer (CRC) incidence, mortality, and post-colonoscopy CRC. The guideline highlights the need for future research in diverse populations and settings, particularly regarding detection of clinically significant polyps, cost-effectiveness, patient preferences, and real-world outcomes, with plans to update the recommendation as evidence evolves.
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