Outpatient treatment of diverticulitis with amoxicillin-clavulanate is as effective as treatment with metronidazole plus a fluoroquinolone, according to a study published online February 22 February 22 in Annals of Internal Medicine.
This less commonly used treatment “has the potential to reduce the risk for fluoroquinolone-related harms, including Clostridioides difficile infection [CDI], without adversely affecting diverticulitis outcomes,” study author Anne F. Peery, MD, MSCR, told Medscape Medical News.