New data are challenging a long-held assumption in Crohn’s disease care: that ileal disease is harder to treat than colonic involvement. A post hoc analysis of a phase 3 trial found that subcutaneous infliximab delivered consistent clinical and endoscopic benefits across disease locations—including the terminal ileum—during maintenance therapy. The findings suggest a more uniform treatment effect than many clinicians expect, while also raising questions about how these results will translate outside controlled trials. What surprised investigators most, and what still needs to be proven, is explored in this report from Healio.
Author: Abhay Panchal
Gastroenterology is a highly specialized and rewarding medical field, offering physicians a unique opportunity to blend diagnostic skill with procedural expertise. The demand for skilled GI specialists is consistently high, driven by an aging population, rising rates of digestive diseases, and advancements in screening and treatment. For physicians aiming to build a successful career, understanding the latest clinical trends, technological advancements, and employer expectations is crucial. This guide provides a comprehensive overview of the gastroenterology job market. We will explore the most in-demand subspecialties, the impact of technology on clinical practice, and the essential skills employers are looking for. Whether…
From department chairs and systemwide clinical leaders to national society presidents, gastroenterologists across the country stepped into influential leadership roles in 2025, shaping care delivery, research and professional education. Here are five GI leaders who took on new leadership posts this year: Note: This is not an exhaustive list.
As GLP-1 drugs transform weight loss, a quieter question is gaining urgency: how do patients hold on to those gains once the injections stop? This piece explores a new class of minimally invasive, gut-targeting devices designed to stabilize metabolism after drug-induced weight loss—without weekly shots or lifelong therapy. Early trial results are closely watched, skepticism remains, and multiple approaches are racing toward clinical validation. Whether these one-time procedures represent a durable next chapter in obesity care is becoming one of the most consequential debates heading into 2026, with Fractyl Health emerging as an early contender.
Thirty-two percent of physicians had a secondary income in 2024, according to Medical Economics‘ 96th Physician Report, published Dec. 29. Here’s a breakdown of physician’s additional sources of employment in 2024:
Small, targeted changes to how endoscopy patients are scheduled and processed can have outsized effects on both efficiency and patient experience. Quality improvement work presented at DDW 2025 shows how rethinking arrival times and intake flow helped reduce congestion during peak morning hours, shortened overall time spent in the unit, and improved satisfaction scores—without adding resources. The findings reflect a broader shift toward operational fine-tuning in outpatient endoscopy, where even minutes matter. How these adjustments were designed—and what they revealed about hidden bottlenecks—emerged from the projects led by teams at Mayo Clinic.
Inflammatory bowel diseases (IBD), comprising Crohn’s disease and ulcerative colitis, are chronic, inflammatory, immune mediated, relapsing-remitting conditions of the gastrointestinal tract with multidimensional and often negative effects on patients’ quality of life. The global burden of IBD is increasing and is forecast to affect 1% of the population in early industrialized nations over the next 10 years. Advances in our understanding of the causes and pathogenesis of IBD in the past three decades have translated into new treatments that modulate the immune inflammatory cascade. Modern goals of treatment are clinical remission through assessment of patient reported outcomes and deep remission…
Traditional Medicare is about to change in ways that closely resemble Medicare Advantage—and the shift is drawing sharp scrutiny. Beginning in January, a new pilot program will introduce AI-assisted prior authorization for select procedures across six states, expanding a tool long associated with private plans into traditional Medicare. Supporters frame the move as a way to curb low-value care and reduce waste, while critics warn it could delay treatment and quietly accelerate Medicare’s privatization. With millions of beneficiaries affected and political resistance mounting, the debate over where efficiency ends and access begins is just getting started, as outlined in the…
A new partnership is taking shape around one of colorectal cancer’s most persistent challenges: getting more people screened on time. The Global Healthy Living Foundation and Guardant Health have joined forces to focus on patient-centered education, aiming to reduce confusion, stigma, and access barriers that keep many eligible adults from screening. By elevating patient and clinician voices and pointing to a wider range of screening options, the collaboration hints at a different approach to closing the early-detection gap—one that may influence how and when people choose to get screened.
2025 marked a year of consolidation and momentum in gastroenterology, shaped less by single breakthroughs and more by how rapidly new evidence translated into practice. From a wave of FDA approvals in IBD to evolving guidelines that pushed earlier use of high-efficacy therapies, the field sharpened its focus on durability, flexibility, and patient-centered care. Progress also extended beyond IBD, with advances in pediatric IBS-C, gastroparesis, and colorectal cancer prevention. How these developments collectively reset clinical priorities is explored in this year-in-review from HCPLive.