Disorders of gut–brain interaction (DGBI) often overlap with non-gastrointestinal conditions such as fibromyalgia, headaches, gynecological and urological disorders, sleep disturbances, and chronic fatigue. This complex interplay of symptoms not only complicates diagnosis but also alters treatment approaches and impacts patient outcomes. Recent research from the Rome Foundation Working Team highlights shared pathophysiology between these conditions, although the mechanisms remain unclear.
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