Investigators at Cedars-Sinai have conducted a significant study on inflammatory bowel disease (IBD), identifying key risk factors linked to serious extraintestinal manifestations.
Key points:
- This large-scale study involved over 12,000 subjects and focused on various extraintestinal manifestations of IBD, making it the largest study of its kind to date.
- Researchers examined patients with conditions beyond the gastrointestinal tract, including psoriasis, eye inflammation, and ankylosing spondylitis (affecting the spine or hips).
- Genetic variations and the specific location of IBD in the gastrointestinal tract were associated with the development of these debilitating conditions.
- The study identified factors related to primary sclerosing cholangitis (damaging the liver) and painful peripheral arthritis impacting small and large joints.