Key Points:
- The study found that 56% of patients diagnosed with Barrett’s esophagus (BE) drop off from adhering to proton pump inhibitor (PPI) therapy within a year following their diagnosis.
- Factors contributing to poor PPI adherence include being newly prescribed PPIs, male gender, and the presence of specific comorbidities.
- The research conducted by Charles Gaber, MPH, PhD, and his team involved a retrospective analysis of 79,701 adults diagnosed with BE from a large commercial and healthcare utilization database covering the years 2010 to 2019.
- Patients were predominantly middle-aged (median age of 53), with 57% being male. In the year after diagnosis, adherence patterns varied with 44% showing consistently high adherence, and others showing varying degrees of decline, with some returning to adherence.