An updated meta-analysis of 82 randomized controlled trials, involving 10,332 adult patients with Irritable Bowel Syndrome (IBS), suggests that certain probiotics may improve IBS symptoms.
The study found moderate certainty evidence for the benefit of Escherichia strains, low certainty evidence for some Lactobacillus strains, and very low certainty for combination probiotics, LacClean Gold S, Duolac 7s, and Bacillus strains in addressing global IBS symptoms. However, the researchers emphasized the need for a stronger evidence base before gastroenterologists can confidently recommend probiotics for IBS patients.