Novel test helps identify patients at high risk of esophageal cancers (Medical Xpress)

Johns Hopkins Kimmel Cancer Center has developed Esopredict, a PCR-based test that helps predict the progression of Barrett’s esophagus to esophageal cancer. By analyzing DNA methylation in specific genes, Esopredict identifies patients at higher risk, enabling personalized monitoring and treatment strategies. The test has shown that patients in the highest risk group are 15.2 times more likely to develop high-grade dysplasia or esophageal cancer. This tool aims to improve early detection and reduce unnecessary procedures.