Author: Abhay Panchal

The American Gastroenterological Association (AGA) has released an expert review highlighting immune-mediated and infectious causes of esophageal dysfunction, which extend far beyond GERD. Published in Clinical Gastroenterology and Hepatology, the clinical practice update provides 10 best practice advice statements to help clinicians identify and treat conditions like eosinophilic esophagitis (EoE), systemic sclerosis (SSc), Crohn’s disease, and esophageal infections (Candida, HSV, CMV).

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Despite CMS’s goal for full Medicare and most Medicaid participation in accountable care by 2030, less than half of primary care physicians are joining value-based payment models. Financial constraints, workforce shortages, and excessive documentation remain significant barriers. Fee-for-service still dominates, and small practices lack resources to transition. Physicians support the concept but struggle with implementation, citing unpredictable reimbursement, limited institutional support, and overwhelming quality metrics.

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Gastrointestinal endoscopy is advancing with probe-based confocal laser endomicroscopy (pCLE), achieving 100% sensitivity in adenocarcinoma detection (Quantitative Imaging in Medicine and Surgery). Enhanced Recovery After Surgery (ERAS) protocols cut hospital stays by 30% and boost patient satisfaction to 90% (Journal of Colorectal Surgery). To combat hypoxemia in sedated procedures, nasal clips with nasal cannulas have reduced cases from 25% to 17.7% (BMC Anesthesiology). These innovations are setting new standards in diagnostics, recovery, and patient safety—reshaping GI care.

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In an innovative push to break the stigma around colorectal cancer and encourage early detection, Fondation Digestive and LG2 have launched the ‘Scanitary Paper’ campaign—a toilet paper embedded with a QR code that directs users to Clic Santé to book a stool screening test. This clever initiative, timed for National Colorectal Cancer Awareness Month (March 2025), targets people in the most relevant setting: the bathroom. With 90% of colorectal cancers being curable if detected early, this simple yet effective call to action could save lives.

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The field of gastroenterology is bracing for a worsening physician shortage, with the Health Resources and Services Administration (HRSA) projecting a deficit of 1,390 full-time gastroenterologists by 2037. This alarming trend is fueled by rising patient demand, an aging GI workforce, and burnout-driven attrition, particularly exacerbated by the COVID-19 pandemic. As nearly half of practicing gastroenterologists are over 55, impending retirements threaten to widen the gap, while GI fellowships struggle to replenish the workforce.

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For decades, bioengineers have struggled to design biological systems with the precision of evolution, but Evo 2, a groundbreaking AI model for genomics developed by Arc Institute and NVIDIA, is changing that paradigm. Trained on 9.3 trillion nucleotides across 128,000 species, Evo 2 can predict pathogenic mutations, generate synthetic genomes, and design gene circuits with precision beyond human capabilities. Its unprecedented context window allows it to interpret long-range genetic interactions, addressing one of the biggest challenges in genomics. The model’s potential applications range from custom gene therapies to disease prediction, but its open-source nature also raises ethical concerns about biosecurity.

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Physicians are increasingly turning to side gigs, with 40% now supplementing their income by an average of $34,000 annually, a trend explored in the latest Fixing Healthcare podcast featuring Dr. Jonathan Fisher. Rising burnout, financial strain, and shifts in career fulfillment are fueling this change, as doctors move from independent practice to hospital employment and grapple with the growing role of AI in healthcare. With medicine becoming less intellectually stimulating, many physicians seek creative and financial outlets beyond traditional practice. The episode raises a crucial question: Is this a symptom of a broken system, or the future of medical careers?

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The Crohn’s & Colitis Congress 2025 unveiled groundbreaking advancements in IBD care, from AI-driven disease monitoring and non-invasive sweat-based diagnostics to evolving guidelines on pregnancy and obesity management. Experts emphasized the importance of medication adherence during pregnancy, the potential of GLP-1 drugs in IBD treatment, and the role of bariatric surgery in disease outcomes. Meanwhile, AI innovations like IBD Aware and Smart Notes are set to transform patient monitoring and clinical workflows. With these cutting-edge developments, the future of IBD care is shifting rapidly—but the real question remains: Are we ready to embrace this revolution in precision medicine?

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