Big Tech is no longer experimenting with healthcare—it’s competing to own the patient’s first interaction.
Amazon, OpenAI, and Perplexity are rapidly launching AI-driven health platforms that sit before the clinic—handling symptoms, interpreting labs, guiding decisions, and even routing care.
This isn’t one product category—it’s a stack war:
- Amazon is building vertically—AI + providers + pharmacy + referrals in one closed loop
- Perplexity is aggregating horizontally—connecting EHRs, wearables, and lab data into one interface
- OpenAI brings scale—hundreds of millions already asking health questions weekly
And the behavior shift is already here:
👉 3 in 5 adults are using AI for health
👉 Most interactions happen outside clinic hours
👉 AI is becoming the default first touchpoint—not the doctor

