New guidance from the American Gastroenterological Association recommends that physicians consider de-prescribing proton pump inhibitors (PPIs) for any patient on chronic PPIs without a clear indication, and step-down dosing for those on twice-daily treatment.
The expert review focuses on three domains: documentation of an indication for PPI usage, identification of suitable candidates for whom de-prescribing may be appropriate, and how to successfully go about de-prescribing.