Endoscopic submucosal dissection and endoscopic mucosal resection with margin ablation should be considered standards of care to reduce recurrence after endoscopic resection of large colorectal polyps, according to a new study.
The systematic review and meta-analysis found that local recurrence rates are significantly lower after these procedures than they are with standard endoscopic mucosal resection (EMR).
“The optimal resection method for polyps 10 mm or larger has been a matter of debate with the emergence of new resection techniques,” said principal investigator Roupen Djinbachian, MD, a resident at the University of Montreal. “Given this gap in our knowledge, we decided to compare all these techniques in a meta-analysis.” In addition to standard EMR, endoscopic submucosal dissection (ESD) and EMR with margin ablation, these techniques include cold snare polypectomy, cold snare EMR and underwater EMR.