Three Takeaways for the Future of GI
1. Cancer Screening Enters a New Scale Phase
Abbott’s acquisition signals a structural shift: early cancer detection (MCED, MRD, noninvasive screening) is moving from emerging innovation to mass-market scale.
With Abbott’s global distribution, regulatory experience, and manufacturing capacity, adoption will accelerate far beyond what Exact could have achieved independently.
2. Cologuard Just Got a Global Engine Behind It
Expect a dramatic expansion of both Cologuard and Cologuard Plus—driven by:
- deeper integration into primary care workflows
- international expansion across markets where Exact had limited reach
- broader adoption among employers, payers, and health systems
For GI practices, this means a larger population entering screening earlier, often before they reach specialist care—reshaping referral patterns and CRC prevention strategies.
3. Abbott Is Playing the Long Game
Exact adds >$3B in revenue and high-teens growth, pushing Abbott’s diagnostics division above $12B annually.
The company is willing to absorb EPS dilution through 2027 because it sees cancer diagnostics as a multi-decade growth engine—and wants to own global category leadership from screening to precision oncology.

