At the 2025 AGA Tech Summit, an unexpected innovation stole the show—and it wasn’t AI or robotics. It was Twistomy, a low-profile, twist-to-empty ostomy device designed to replace the traditional pouch system that hasn’t evolved in 70+ years. Created by Devon Horton and Lily Williams from the University of Colorado, the device aims to eliminate leaks, odors, and the emotional toll of current systems.
Judges unanimously voted Twistomy the Shark Tank winner, calling it a “deeply empathetic solution” that could save $80,000 per patient in complications. With FDA approval on the horizon and a 3D-printed prototype already tested, the team envisions a future where ostomy users can finally regain control—quietly, confidently, and on their own terms.