- Blood-based screening, also known as a “liquid biopsy,” is being considered as an alternative screening method for colorectal cancer (CRC), particularly for patients who avoid established screening tests like colonoscopy.
- While blood-based tests might be more convenient for some patients, they have higher rates of false positives and false negatives compared to colonoscopy, potentially leading to more undiagnosed cases and deaths from CRC.
- David Lieberman, MD, chair of the American Gastroenterological Association’s CRC Workshop Panel, emphasizes that based on current characteristics, blood tests should not replace established screening tests due to their lower effectiveness and cost-effectiveness.
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