For decades, bioengineers have struggled to design biological systems with the precision of evolution, but Evo 2, a groundbreaking AI model for genomics developed by Arc Institute and NVIDIA, is changing that paradigm. Trained on 9.3 trillion nucleotides across 128,000 species, Evo 2 can predict pathogenic mutations, generate synthetic genomes, and design gene circuits with precision beyond human capabilities. Its unprecedented context window allows it to interpret long-range genetic interactions, addressing one of the biggest challenges in genomics. The model’s potential applications range from custom gene therapies to disease prediction, but its open-source nature also raises ethical concerns about biosecurity.
Evo 2 Can Design Entire Genomes (Asimov Press)
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