An industry-first FDA approval for a nonalcoholic steatohepatitis (NASH) therapy may still be a ways off. After reviewing Intercept Pharmaceuticals’ latest application for obeticholic acid (OCA), the agency appears all but ready to reject the drug in NASH-related pre-cirrhotic liver fibrosis, according to a briefing document released ahead of an expert panel meeting set for Friday. Citing a long list of safety risks and the practical hurdle for patients to undergo a liver biopsy—coupled with “modest” efficacy—the FDA said it “cannot justify OCA use in NASH subjects with stage 2 or 3 fibrosis.”
Author: Rutali Thakur
AbbVie wants to remind people about the importance of honest discussions in inflammatory bowel disease (IBD) with the kickoff of a new YouTube conversation series. The global “Gutsy IBD Conversations” campaign will include Twitter, Facebook and LinkedIn and channel shorter content posts to help drive viewers to the full series on YouTube. The first episodes officially debut on Friday, which is World IBD Day, and a total of 15 short-form video conversations will be released throughout May and June,
Oshi Health, the virtual specialty care company transforming gastrointestinal (GI) health outcomes and economics, has been selected by Modern Healthcare as one of the 2023 Best Places to Work in Healthcare. “We are scaling access to care that millions of people have desperately needed, and building a specialized clinical workforce and empowered culture that thrives through virtual care delivery. This opportunity to change lives is what drew all of us to healthcare in the first place,” said Sam Holliday, Oshi Health CEO. “We are honored to be included in Modern Healthcare’s Best Places to Work and are grateful for our team’s…
Scientific evidence, not popular ideas, should drive probiotic and prebiotic recommendations in clinical settings. Globally, evidence is continually emerging on how probiotics and prebiotics can be effectively used in patient care but health care professionals often struggle to find out where the evidence stands for a particular condition. The World Gastroenterology Organization (WGO) recently published an updated guideline document, aimed at helping gastroenterologists and other physicians understand appropriate clinical applications for probiotics or prebiotics. The guideline was created with contributions from experts in gastroenterology, probiotics, and prebiotics, with the efforts co-led by experts from the International Scientific Association for Probiotics…
Following plans to file for Chapter 11 bankruptcy, Envision Healthcare reached a restructuring agreement with its stakeholders. Under the agreement, AmSurg and Envision Physician Services will be separately owned by their lenders, Envision said in a May 15 news release. AmSurg will buy ASCs held by Envision for $300 million plus a waiver of loans.
Reports record results, raises full-year guidance, accelerates path to positive free cash flow First quarter highlights MADISON, Wis., May 9, 2023 /PRNewswire/ — Exact Sciences Corp. (Nasdaq: EXAS), a leading provider of cancer screening and diagnostic tests, today announced that the company generated revenue of $602.5 million for the first quarter ended March 31, 2023, compared to $486.6 million for the same period of 2022.
We write tons of detailed articles about niche topics, for our seasoned audience. However, every now and then it is important to zoom out and just look at the big picture as well. Here we decided to provide a high-level outlook of what’s coming next for AI in healthcare, and hope it will be useful. So let’s take a birds-eye view of what we can expect from AI in healthcare in the coming period. In this post, we will not discuss abstract principles but will instead focus on providing specific examples. By examining recent advancements and exploring potential future developments,…
As the number of cases of early-onset colorectal cancer (CRC) diagnosed before age 50 continues to rise, early detection has become increasingly important. A new study has identified four signs and symptoms that can serve as red flags to facilitate earlier detection of early-onset CRC. The signs and symptoms are abdominal pain, rectal bleeding, diarrhea, and iron-deficiency anemia. Two symptoms in particular ― rectal bleeding and iron-deficiency anemia ― point to the need for timely endoscopy and follow-up, the researchers say. “Colorectal cancer is not simply a disease affecting older people; we want younger adults to be aware of and act on these potentially very telling…
CHICAGO — Patients with nonalcoholic fatty liver disease had worse COVID-19-related outcomes compared with infected individuals without NAFLD, according to data presented at Digestive Disease Week. “The COVID-19 pandemic is one of the most significant global public health crises in recent history,” Khaled AlsabbaghAlchirazi, MD, clinical assistant professor of medicine at Cleveland Clinic, told Healio. “Obesity and other metabolic factors can exacerbate the severity of COVID-19. NAFLD is the most common chronic liver condition in the United States and is considered a hepatic manifestation of the metabolic syndrome.”
In the half-century since the first colonoscopy was performed in 1969, the procedure has become a mainstay for managing colorectal cancer screening and assessing bowel symptoms.1 In the United States alone, approximately 16 million colonoscopies are performed annually.2 Given that in the majority of cases the indication for the procedure is colon cancer screening or polyp surveillance, patients opt in to the procedure as a means of prevention. Colonoscopies are not without complications, including infection, bleeding, perforation, and, more rarely, splenic injury. Although all-cause colonoscopy complications only occur at a rate of 0.28%, morbidity and mortality from splenic injury in particular…