The first quarter of 2025 brought significant advances in gastroenterology, including FDA approvals for mirikizumab and guselkumab, expanding treatment options for Crohn’s disease. Apraglutide’s rolling NDA submission also raised hope for patients with short bowel syndrome. Promising clinical trial data emerged for fecal microbiota transplantation in type 1 diabetes-related gastroenteropathy and icotrokinra for ulcerative colitis. In colorectal cancer screening, annual FIT testing was validated as the most effective and cost-efficient method for low-adherence populations.
Author: Abhay Panchal
Australian researchers at the University of South Australia, in collaboration with Ferronova, are pioneering a quantum sensor-powered laparoscopic probe that could revolutionize how gastrointestinal cancers are detected and treated. Backed by a $405,050 government grant, this minimally invasive tool works with iron-oxide nanoparticles (FerroTrace) to precisely map cancerous lymph nodes, potentially sparing patients from extensive surgeries and long-term side effects. Unlike traditional radioactive tracers, this innovation offers a safer, more targeted approach—especially valuable for patients undergoing chemo or radiation therapy. Interestingly, the same technology showed remarkable promise in oral cancer trials, where it helped pinpoint hidden tumors with uncanny accuracy—like…
Innovative drug delivery systems like nanoparticles, hydrogels, and microgrippers are transforming gastrointestinal treatment—particularly for IBD—by enabling precise, sustained, and targeted therapeutic delivery. These technologies aim to overcome GI tract barriers, improve patient adherence, and offer personalized, efficient disease management solutions.
Neurogastroenterology (NGE), the subspecialty focused on disorders of gut-brain interaction (DGBIs) such as IBS and chronic constipation, faces limited growth due to inadequate training, lack of referral centers, and persistent stigmas within the medical community. Despite their high prevalence and burden on healthcare systems, DGBIs remain underrepresented in curricula and poorly resourced, especially in countries like Italy, where surveys reveal insufficient diagnostics and clinical infrastructure. Expanding education, multidisciplinary care, and institutional support is essential to improve patient outcomes and attract more young gastroenterologists to the field.
Teladoc Health has launched a next-generation Cardiometabolic Health Program aimed at preventing and managing diabetes, hypertension, and obesity by addressing key lifestyle and biomarker metrics such as diet, sleep, stress, and blood pressure. The enhanced program includes personalized coaching, at-home testing, connected device integration, and places 100% of program fees at risk, reflecting Teladoc’s confidence in improving population health outcomes.
Once hyped and then humbled, the microbiome therapeutics field is entering a promising new phase, driven by FDA approvals, improved clinical trial outcomes (particularly in C. difficile and GvHD), and advances in manufacturing and automation. Despite ongoing regulatory and commercialization hurdles, the sector is poised to evolve from a niche concept into a foundational pillar of precision medicine, offering scalable, data-driven treatments for complex conditions like IBD and metabolic disorders.
mBIOTA Labs announced promising results from the first prospective clinical trial of its elemental diet, mBIOTA Elemental™, showing high effectiveness in treating SIBO and IMO with a 100% patient compliance rate and up to 83% eradication of SIBO. The palatable formula also led to 82% symptom improvement, notable visceral fat loss, and reduced brain fog, setting a new standard for tolerability and outcomes in elemental nutrition for GI disorders.
GI Partners of Illinois has partnered with Athelas to adopt its AI-powered revenue cycle management (RCM) platform. This collaboration aims to streamline claims processing, cut denials, and enhance financial performance while allowing the practice to focus more on patient care.
In this episode of the CEO Podcast, we chat with Beth Houck, the passionate and driven CEO of SonarMD. Beth takes us through her inspiring journey—from being the right-hand person at several startups to finally stepping into the CEO role in 2021. She opens up about the highs and lows of leading a healthcare startup, how SonarMD is changing the game in managing inflammatory bowel disease (IBD), and why company culture is at the heart of everything she does.
What happens when a data scientist with IBS meets a digital health operator scaling virtual GI care? You get more than an acquisition—you get a glimpse of where gastroenterology is headed.On this episode of The Scope Forward Show, Asaf Kraus (founder of Dieta Health) and Bill Snyder (founder & CEO of Cylinder Health) join me to announce Dieta’s acquisition. But we didn’t stop at the deal. We talked AI, clinical outcomes, and why digestive health—despite affecting millions—remains underrecognized in digital health. Cylinder has already served 100,000 patients. GI care represents a $136 billion market, mostly buried in fragmented smaller markets. That’s starting to change.Asaf’s…