First Wave BioPharma’s bid to challenge AbbVie for a gastrointestinal market has suffered a setback, with the biotech telling investors “it is likely the primary efficacy endpoint was not achieved.” Florida-based First Wave is developing a formulation of adrulipase, a yeast-based alternative to AbbVie’s Creon and other pig-derived pancreatic enzyme replacement therapies. The therapies are used to treat nutritional deficiencies related to conditions including cystic fibrosis. First Wave bet its enzyme is a safer option with a lower pill burden and simplified sourcing that eliminates the risk of pathogen transmission.
Author: Abhay Panchal
CHICAGO—For managing colorectal lesions not sufficiently treated with a first attempt, endoscopic submucosal dissection achieved high rates of en bloc and R0 resection with low rates of local recurrence and perforation in a largely North American patient population. “Salvage ESD is highly effective for the treatment of previously attempted colorectal lesions (PACL),” said Suchapa Arayakarnkul, MD, a post-doctoral research fellow at the Johns Hopkins Hospital, in Baltimore. “When ESD is performed by experts, adverse events are uncommon and most can be managed endoscopically. The results of our study support the role of ESD for PACL in the Western setting.”
A patient with long-standing irritable bowel syndrome came to her gastroenterologist after a flare, indicating that she had stopped responding to her medication She didn’t know what to do with the stress anymore and wanted to try a more natural method. The physician looked at her blankly and said, “We don’t offer any of that here.” We can do better.Chronic gastrointestinal disorders can be multi-faceted, and patients may not always respond to conventional care. I think we can all agree that psychosocial factors have a profound impact on GI functioning and there is mounting evidence supporting the negative impact that…
In this podcast episode, Tamara Duker Freuman, MS, RD, CDN, discusses how the work of gastroenterologists and dieticians can inform each other, approaching GI conditions as new science emerges and more.
The artificial intelligence chatbot ChatGPT can potentially be used as source of information for patients, as well as an aid to clinicians managing gastroesophageal reflux disease (GERD), a study has found. The researchers say the tool’s conversational format could improve clinical efficiency and reduce the volume of patient messages and calls, potentially diminishing clinician burnout. However, inconsistencies and content errors observed require a certain level of clinical oversight, caution the researchers, led by Jacqueline Henson, MD, with the Division of Gastroenterology, Duke University School of Medicine, Durham, North Carolina.
Exton, Pennsylvania, July 18, 2023 (GLOBE NEWSWIRE) — Data from the Centers for Disease Control & Prevention (CDC) suggests just over seventy percent of American adults are overweight, including 40% being clinically obese. Nearly twenty percent of children are obese, rising from 12% of those 2-5 years of age to over 22% of those 12-19 years of age. Analysis from the NIH identified the origin of the US obesity epidemic starting in the late seventies, when the prevalence was roughly 15%, rising steadily through the turn of the century to 30% and continuing to present day. Worldwide, the rise of…
In the newest episode of Small Talk, Big Topics, hosts Drs. Matthew Whitson and Nina Nandy are joined by Drs. Jessica Korman and Erica Cohen, gastroenterologists from Capital Digestive Care, a gastroenterology group located in the Washington, D.C.-area to discuss working in private practice, including managing challenging cases.
Over the past decade, a significant percentage of the country’s physicians have shifted from working in private practices (defined as those owned wholly by physicians) to working in bigger, health system-owned practices. The ability to negotiate higher payment rates with insurers when working at a larger practice is a crucial factor causing this trend, according to a new AMA analysis.
The American College of Gastroenterology recently released an updated clinical guideline on the management of acute lower gastrointestinal bleeding (Am J Gastroenterol 2023;118[2]:208-231). GEN’s Sarah Tilyou spoke with lead author Neil Sengupta, MD, a gastroenterologist and associate professor at the University of Chicago Medicine, about the impetus for the guideline and what it means to GI practice.
Omeprazole is the most frequently prescribed gastroenterology prescription, according to April 13 data from Definitive Healthcare, making up 17.60 percent of all prescribed GI medications.The top 15 most prescribed GI medications and the percentage of prescriptions: