While artificial intelligence has already proven its value in GI diagnostics—boosting polyp detection, improving histology scoring, and streamlining endoscopy—this review argues that its real transformative potential lies elsewhere: helping patients actually follow the diet and lifestyle changes that matter most.
For conditions like IBS, IBD, GERD, celiac disease, and functional GI disorders, diet is often more effective than drugs. Yet adherence remains poor due to limited access to dietitians, lack of personalization, cultural mismatch, and zero real-time support. The result? Patients turn to trial-and-error or unreliable online advice.
AI offers a way out of this gap. Using natural language processing, predictive analytics, chatbots, wearables, and microbiome data, AI-driven systems can deliver personalized, culturally relevant, real-time dietary guidance—outside the clinic. Early evidence shows AI-supported nutrition tools can improve adherence, reduce symptoms, enhance microbiome diversity, and deliver outcomes comparable to in-person care.
The article envisions a future where AI-powered diet apps, symptom trackers, and digital therapeutics evolve into FDA-cleared, reimbursable tools—integrated with wearables and biomarkers to predict flares before they happen. Instead of episodic GI care, patients could receive continuous, proactive support tailored to their biology, lifestyle, and culture.