The American Gastroenterological Association’s 2025 clinical guidance reflects a clear shift toward risk-based, personalized, and technology-enabled GI care—aimed at helping clinicians deliver higher-quality outcomes while navigating growing complexity in practice.
In its year-in-review update, AGA highlights a broad set of evidence-driven guidelines and clinical practice updates designed to translate rapidly evolving research into practical decision-making at the bedside.
Among the top clinical practice updates, AGA addressed everyday yet high-impact challenges, including optimized screening and vaccination strategies for patients with IBD, guidance on portal vein thrombosis, and updated approaches to gastric cancer prevention. New recommendations also tackle less common but often under-recognized conditions such as sclerosing mesenteritis and GI manifestations of hypermobile Ehlers-Danlos syndrome—underscoring AGA’s effort to close diagnostic gaps and standardize care across diverse patient populations.