The World Gastroenterology Organisation has introduced a new “Global Cascade Approach” to managing chronic constipation—one of the most common yet variable GI disorders worldwide. Rather than prescribing a rigid gold-standard, the guideline offers a tiered, resource-sensitive framework that adapts to diverse healthcare environments, from primary care to specialized GI practice. With prevalence rates affecting up to one in five people globally, this landmark update could reshape how clinicians diagnose and treat patients across different settings.
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