Viome and Scripps Research to develop precancerous colon polyps’ detection test (Medical Device Network)

Viome Life Sciences and Scripps Research have partnered to develop the first RNA-based at-home test to detect precancerous colon polyps—aiming to shift CRC prevention from invasive colonoscopy to early molecular detection.

Key details:

• Uses Viome’s AI + RNA sequencing platform, adapted from its FDA-designated CancerDetect Oral & Throat test
  
• Trial to begin this year with 1,000 participants undergoing colonoscopy at Scripps
  
• Collects stool and saliva samples pre-procedure to train AI on early polyp biomarkers
  
• Initial distribution as an LDT via licensed physicians, with future FDA clearance plans
  
• Seeks to empower earlier intervention by detecting cancer risk before symptoms arise
  

If successful, this could mark a major advancement in noninvasive CRC prevention by targeting polyp-stage intervention.