The article titled “‘Small difference’ in colorectal neoplasia recurrence at 5 vs. 10 years after polypectomy” from Healio, authored by Kate Burba, discusses a study on the recurrence rates of advanced colorectal neoplasia (ACN) following polypectomy.
Here’s a summary of the key points:
- The study found that the rates of advanced colorectal neoplasia recurrence were 1.5% at 5 years and 2.42% at 7 to 10 years after polypectomy.
- Factors such as older age, male sex, and the absence of diabetes or cardiovascular disease were significantly linked with recurrence.
- The study supports performing surveillance colonoscopy 7 to 10 years after the detection and removal of baseline non-advanced adenoma, rather than at 5 years.
- The research was a territory-wide, retrospective cohort study conducted in Hong Kong, involving 109,768 individuals who underwent polypectomy for non-advanced adenoma (NAA) at a baseline colonoscopy between 2008 and 2018.
- The primary outcome measured was the recurrence of advanced colorectal neoplasia at surveillance colonoscopy performed 5 years vs. 7 to 10 years after baseline.
- The study concluded that there is a small difference in the recurrence of ACN between individuals who received colonoscopy workup at 5 years versus 7 to 10 years. This supports a 7- to 10-year surveillance period after baseline NAA was polypectomized.
- The findings could help in formulating future guidelines and consensus statements on the optimal surveillance interval following the diagnosis of newly diagnosed NAA in people at risk for ACN.
The study emphasizes the importance of determining appropriate surveillance intervals post-polypectomy to promote best practice in screening for colorectal neoplasia.