A breakthrough study published in Clinical and Translational Gastroenterology, the official journal of the ACG, showcases ProPhase Labs’ BE-Smart — an 8-protein, mass-spectrometry-based assay that accurately predicts which Barrett’s esophagus patients are likely to develop esophageal cancer. Developed with the Mayo Clinic, BE-Smart achieved 100% sensitivity and a hazard ratio of 66, marking a major leap in molecular risk stratification. The test requires minimal tissue and works with standard biopsies, offering a scalable, next-generation approach for early cancer detection. Early access and physician programs are set to launch in early 2026.
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