A multicenter randomized trial in Japan shows that real-time peripheral gaze guidance significantly improves adenoma detection rate (ADR) during colonoscopy — without increasing withdrawal time.
In the EYE-SIGHT trial (n=400), patients were randomized to standard colonoscopy or an eye-tracking feedback (ETF) system that prompted endoscopists to scan the periphery of the monitor.
Key Results
- ADR: 53.3% (ETF) vs 39.2% (control)
- Adenomas per colonoscopy (APC): 1.34 vs 0.95
- Polyp detection rate: 66.5% vs 47.2%
- Withdrawal time: No significant difference
Notably, detection improved for:
- 5–9 mm adenomas
- Flat-type adenomas
- Left-sided lesions
Advanced adenoma detection and sessile serrated lesion detection did not significantly change.