Multitarget Stool DNA Tests Often Not Completed (Medscape)

A recent analysis from the University of Pittsburgh Medical Center highlights that nearly half of patients prescribed multitarget stool DNA (mt-sDNA) tests for colorectal cancer (CRC) do not complete them, revealing critical gaps in compliance that disproportionately affect certain populations. The study reviewed 91,664 mt-sDNA orders from 2017 to 2021 and found an overall completion rate of 54.7%, with lower rates among Black patients (38.8%) compared to White (54.1%) and Asian patients (56.9%). Repeat test orders also correlated with decreased completion, dropping to 32% for patients with three or more orders.