Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract (Nature)

The incidence and prevalence of inflammatory bowel disease (IBD), the chronic inflammation of intestinal tissues¹, have risen dramatically in recent decades². In 2015, an estimated ~1.3% of U.S. adults (~3 million) were diagnosed with IBD³, representing a 50% increase from 1999 (~2 million)⁴. IBD can severely impact life quality, as symptoms include abdominal pain, diarrhea, and rectal bleeding, and there is no cure.