In this edition of “Sharma’s Endoscopy Insights,” I highlight two studies related to resection—an approach to ulcerative colitis–related lesions and a through-the-scope suturing system for closing mucosal defects after endoscopic resection—and a third study on palliation of dysphagia for patients with advanced esophageal cancer.
Patients with long-standing UC can develop neoplasia. Several cases of endoscopic treatment have been reported. In this retrospective series, investigators reported success using endoscopic mucosal resection and endoscopic submucosal dissection for a patient population with UC-associated neoplasia but point out the potential for adverse events associated with endoscopic approaches, as well as the development of metachronous lesions.
After the removal of large lesions in the colon, such as laterally spreading tumors, closure of the mucosal defect sometimes is required. It has been accomplished traditionally using clips. Now, a new through-the-scope suturing system may be applicable in such situations.