Cell-Free DNA Blood Test Developed for Detecting Colorectal Cancer (MDedge)

This study highlights the effectiveness of a new cell-free DNA (cfDNA) blood test in detecting colorectal cancer (CRC):

1. The cfDNA test accurately detected CRC in the majority of confirmed cases.
2. It showed 83% sensitivity for CRC, 90% specificity for advanced neoplasia, and 13% sensitivity for advanced precancerous lesions. This compares favorably with other noninvasive methods.
3. According to Dr. William M. Grady, the test is a significant step towards more convenient early CRC detection methods.
4. It offers a similar accuracy rate for colon cancer detection as stool tests, providing a viable alternative for those reluctant to undergo current screenings.
5. Conducted across 265 U.S. sites, the study involved 7861 people with average CRC risk, comparing the cfDNA test against colonoscopy.