This first-ever ACG guideline addresses gastric premalignant conditions—including atrophic gastritis, gastric intestinal metaplasia (GIM), dysplasia, and certain epithelial polyps—due to their potential progression to gastric adenocarcinoma (GC). Although the U.S. is a low-incidence country for GC, certain non-White and immigrant populations experience significantly higher rates, making GC an underrecognized health disparity.
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