Imagine diagnosing upper GI bleeding without an endoscopy. A new ingestible capsule, PillSense, is doing just that—providing real-time detection of gastrointestinal blood in just 10 minutes. In a study presented at DDW 2025, this FDA-approved tool not only proved safe and highly accurate but also altered clinical decisions in 80% of cases.
Patients with negative results had dramatically shorter hospital stays, fewer transfusions, and avoided unnecessary EGDs—all with no adverse outcomes. With hospital resources stretched thin, this tiny device could help triage patients faster, reduce costs, and prioritize care for those truly in need.
But is it the end of traditional endoscopy—or just a smarter way to decide when it’s actually needed?